This is our official list of the best 5-HTP products on the market today. Scroll further down or click “More Info” for full details on each product.
|#1||NOW Foods 5-HTP||Lowest Price More Info|
|#2||Thorne Research 5-Hydroxytryptophan||Lowest Price More Info|
|#3||Nutrigold 5-HTP Gold||Lowest Price More Info|
|#4||Doctor’s Best 5-HTP Enhanced||Lowest Price More Info|
|#5||Solaray 5-HTP||Lowest Price More Info|
|#6||Pure Encapsulations 5-HTP||Lowest Price More Info|
|#7||Integrative Therapeutics 5-HTP||Lowest Price More Info|
|#8||Douglas Labs 5-HTP||Lowest Price More Info|
|#9||Designs For Health 5-HTP Synergy||Lowest Price More Info|
|#10||Just Potent 5-HTP||Lowest Price More Info|
Most Effective 5-HTP Products Reviewed
This is very inexpensive in comparison to the others and is a very popular brand. This has helped people with anxiety, relaxation and recovering from depression. Some people say that if they take this on an empty stomach, they become nauseous.
- 5-HTP (5-hydroxytryptophan) (from Griffonia simplicifolia extract) 100 mg
- Rice flour
- Cellulose (capsule)
The Thorne Research 5-Hydroxytryptophan supplement is quite a bit less expensive than the top two products on this list. Part of the reason for that is because this supplement has a lower dosage. These pills are quite small and easy to ingest. It contains soy, so those with allergies should avoid this product. Some people claim that this product gave them eczema.
- Vitamin B6 (as pyridocal 5′-phosphate) 6.8 mg
- 5-Hydroxytryptophan 100 mg
- Microcrystalline cellulose
- Hypromellose (derived from cellulose) capsule
- Silicon Dioxide
According to the makers of this product, this is an “exceptionally pure extract free of solvents and Peak-X.” Peak X is a contaminant that has been found in certain brands of 5-HTP that causes fatigue, numbness and severe muscle pain. Some people report feelings of nausea when taking these capsules, but most say that it is very effective.
- 5-HTP 100 mg
- Rice concentrate
- Vegetable compound
Doctor’s Best 5-HTP contains vitamins B6 and C. Both vitamins are crucial to the conversion process of turning 5-HTP into serotonin. These should not be taken right before bedtime. It’s best to take one in the morning and one in the early afternoon. One rather odd side effect is that some people report having lucid dreams after taking it.
- Vitamin C 200 mg
- Vitamin B6 15 mg
- 5-hydroxyl L-tryptophan 100 mg
- Modified cellulose (vegetarian capsule)
- Rice powder
- Magnesium stearate
Solaray is a bit of an oddity. It has 50 mg in a capsule, which is much less than most of the other brands. There is nothing on the label that says it is free of gluten or soy, so you should assume that there is some in it. These taste a little funky. These pills are a very good value and are probably best for people with slight sleeping problems.
- L-5-hydroxytryptophan (as griffonia simplicifolia seed extract) 50 mg
Pure Encapsulations makes an effective and simple 5-HTP product. It is more expensive than most 5-HTP supplements, but those who take it rave about it. Those who have taken it report that it helps them to sleep normally. Some say that they stopped taking antidepressants and took this instead and it worked. Anyone considering doing such a thing must consult a doctor first.
- 5-hydroxytryptophan (Griffonia simplicifolia) 150 mg
- Hypoallergenic plant fiber (cellulose)
- Vegetarian capsule (cellulose, water)
These come in vegetarian capsules and contain rice flour, which is not the optimal delivery method. People have reported that it works well as a sleep aid and that it is effective at alleviating depression, OCD symptoms and that it aided their digestion issues. This product contains no dairy, soy, sugar, wheat or yeast.
- L-5-Hydroxytryptophan 50 mg
- Rice flour
- Vegetable capsule (modified cellulose)
Douglas Labs makes a very direct and effective 5-HTP supplement. Many who take it say that it works very well and have no complaints whatsoever. This product is free of gluten and dairy.
- L-5-Hydroxyltryptophan 150 mg
- Vegetable stearate
Designs For Health 5-HTP are much more expensive than most other 5-HTP brands and they don’t really work that much better. Those who take it say it has helped with getting restful sleep and is an effective appetite suppressant.
- Vitamin B-6 (as Pyridoxal-5-Phosphate 10 mg
- 5-HTP (5-Hydroxytryptophan) 50 mg
- Microcrystalline cellulose
Just Potent 5-HTP is an affordable supplement that contains vitamin b6 for added effect. This product has worked well on people with migraines and those with sleep problems. Each capsule is 200 mg, which means that you must take two of them per day. These bottles won’t last as long as others. Consumers should be aware that a certain percentage of people who take this product report that it gives them headaches and severe nausea.
- 5-hydroxytryptophan (seed) extract 400 mg
5-HTP Supplements Guide
What is 5-HTP?
5-HTP stands for 5-Hydroxytryptophan, a substance that can raise serotonin levels in the brain. High serotonin levels cause a person to feel happier, gain appetite control and get into a stable sleep routine. Serotonin is a neurotransmitter that handles endocrine and is responsible for emotion, appetite and sleep cycles.
Boosting serotonin can be done in a few different ways. Serotonin levels are affected by certain foods, such as eggs and turkey. Turkey in particular is loaded with tryptophan, which is part of what makes up 5-HTP. Doctors often prescribe anti-depressants to raise serotonin levels.
It is almost impossible to regulate serotonin through food, and prescription medications often have severe side effects. Some people prefer to use 5-HTP supplements because they do not have side effects and are very effective in the majority of cases. There are often times when a doctor will direct a patient to a 5-HTP product rather than a prescription anti-depressant.
People take 5-HTP to help improve their mood, to fix their sleeping cycles and to control their eating habits. 5-HTP can help people fall asleep faster and stay asleep. Those who are not depressed should not take 5-HTP, as it is a substance that must be taken over the long haul and there are simpler ways to get to sleep.
The National Institute of Health has declared that 5-HTP is possibly unsafe. This is because some batches of 5-HTP contained peak X, a contaminant that led to an outbreak of eosinophilia-myalgia syndrome. Those who have suffered through EMS report experiencing disabling muscle pain and neurotoxic reactions.
Things to Look for in a Good 5-HTP Supplement
When looking at the ingredients, generally the best supplements won’t have fillers or chemicals. They’ll have 5-HTP in a large dose like 150 mg or 200 mg and little else. It is always a good idea to check the reviews. If a product has reviews where people say they got sick, those products should be avoided as they might have contaminants. If 5-HTP is taken and there are strong feelings of nausea, stop taking it.
The dosages vary wildly in each product. It is very important to always read the label. Also keep in mind that supplements like these are under less strict regulations so research should be done before deciding on which brand to buy. The market is flooded with products and many of them don’t have any beneficial effects at all aside from the placebo effect.
How to Take 5-HTP Supplements
Most 5-HTP supplements recommend that you take 1 to 3 capsules per day, each consumed before a meal. These products are not meant to be taken as-needed. You need to take it every day. The effects roll out over the course of a few weeks. This is along-term drug not meant be taken occasionally.
It is extremely important to keep in mind that you should follow the instructions carefully. If you take more than recommended you will become emotionally unstable and it might last for quite a while.
Those who have bipolar disorder should not take 5-HTP as it will amplify manic phases. A small percent of those who take this have vivid dreams, a loss of appetite and actually become depressed. If you experience these symptoms, discontinue use and consult a physician immediately.
Some have said this has effected their libido in a negative way. Some who stopped taking it report feeling very down and some have even suffered anxiety attacks.
People who are taking prescription anti-depressants should not use this product. Those with gastrointestinal issues might experience cramping or nausea.
These should not be taken by pregnant or lactating women. It should not be used with SSRI medications or MAO inhibitors. Children should never take 5-HTP.