The Best Alpha-GPC Supplements – Top 10 Brands Ranked for 2019

This is our official list of the best selling alpha-GPC products on the market right now.

These 10 alpha-GPC brands have been ranked because they dominate the e-commerce sales charts, fitness bloggers love them and they have the highest user reviews online.

Top 10 Alpha-GPC Products Compared

Heads up, there are affiliate links in this article, so if you buy something, we get a cut of the sale.


1. Now Foods Alpha GPC

Now Foods Alpha Gpc

NOW Foods Alpha GPC offers a good alpha GPC dosage delivered in vegetarian capsules free from gluten and many other allergens, such as milk, egg and fish. At 300 mg per capsule taken twice daily, this high-quality alpha GPC supplement is a good choice for many.

Specs

  • 600 mg alpha GPC
  • Two capsules per serving
  • 30 servings per container
  • Free from many allergens
  • Vegan/vegetarian
  • Gluten-free
  • Good Manufacturing Practices (GMP) certified
  • Good customer reviews

Who Makes It?

NOW Foods is a natural health supplement producer that was founded in 1968, and has sustained a reputation for quality, purity and potency in its products. The company uses mostly non-GMO, organic ingredients, and offers a large variety of health products.

Bottom Line

This is the best alpha GPC supplement on the market right now, and its positive customer reviews show it’s well received. It has a good alpha GPC dosage that is vegetarian and free from gluten, and it is made in a GMP certified facility by a reliable brand.

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Where to Buy It
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2. Double Wood Supplements Alpha GPC

Double Wood Supplements Alpha GPC

Double Wood Supplements Alpha GPC is a pharmaceutical grade alpha GPC supplement taken in 300 mg doses twice daily. It is manufactured in the United States and boasts a 100% money back guarantee.

Specs

  • 600 mg alpha GPC
  • Two capsules per serving
  • 30 servings per container
  • Pharmaceutical grade
  • 100% money back guarantee
  • Tested for purity
  • Manufactured in the U.S.A.
  • Good customer reviews

Who Makes It?

Double Wood Supplements is a Philadelphia-based supplement brand offering extracts, essential nutrients and amino acid products. The company makes all of its products in the U.S.A., and tests them for purity.

Bottom Line

This tested, pharmaceutical grade alpha GPC supplement is one of the best, and the manufacturer knows it. They are so confident in it that they offer a 100% money back guarantee. It offers a good alpha GPC dosage of 300 mg twice daily.

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Where to Buy It
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3. Jarrow Formulas Alpha GPC

Jarrow Formulas Alpha GPC

Jarrow Formulas Alpha GPC is a vegan and vegetarian alpha GPC pill offering 300 mg per capsule. It is made free from many allergens, especially gluten. It has 60 servings per container of top-quality alpha GPC capsules.

Specs

  • 300 mg alpha GPC
  • One capsule per serving
  • 60 servings per container
  • Vegan/vegetarian
  • Gluten-free
  • Free from many allergens
  • Good customer reviews
  • GMP certified

Who Makes It?

Jarrow Formulas was founded in 1977 alongside a small health foods store located in West Hollywood, California. Today, the company has grown to offer large variety of dietary supplements made in GMP certified facilities.

Bottom Line

Made in a GMP certified facility by a reliable manufacturer, this high-quality alpha GPC supplement provides 300 mg capsules free from gluten and other allergens. It is vegan and vegetarian, and well-reviewed by consumers, making it one of the best alpha GPC supplements on the market.

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Where to Buy It
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4. VitaMonk Alpha GPC Capsules

VitaMonk Alpha GPC Capsules

VitaMonk Alpha GPC Capsules is manufactured in a GMP certified facility and its ingredients are guaranteed to be 100% premium quality. It offers a 325 mg alpha GPC dosage per capsule, with a total of 60 servings per container.

Specs

  • 325 mg alpha GPC
  • One capsule per serving
  • 60 servings per container
  • GMP certified
  • 100% premium quality guarantee
  • Includes rice flour filler

Who Makes It?

VitaMonk is a health supplements brand that uses traditional health practices and medical research to guide its product formulas.

Bottom Line

With 325 mg per capsule and 60 capsules per container, this 100% premium quality alpha GPC supplement is a good choice. However, it includes rice flour filler.

ⓘ If you buy something using the links below, we get a small commission.

Where to Buy It
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5. Absorb Health Alpha GPC

Absorb Health Alpha GPC

Absorb Health Alpha GPC provides 250 mg per capsule of alpha GPC, made in a GMP certified facility free from cutting agents.

Specs

  • 250 mg alpha GPC
  • One capsule per serving
  • 60 servings per container
  • GMP certified
  • No cutting agents
  • Low dosage
  • Pricey

Who Makes It?

Absorb Health is a newer supplement brand that was founded in 2011 when founder Josh Fulton tried to help his wife Katrina after she fell ill. He saw that many natural supplements could be priced more affordably, and Absorb Health was born.

Bottom Line

This alpha GPC pill offers a lower dosage than most, but it is made in a GMP certified facility using high quality ingredients. It is a bit pricier than some alternatives available on the market.

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Where to Buy It
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6. Douglas Laboratories – Alpha-GPC

Douglas Laboratories Alpha Gpc

Douglas Laboratories – Alpha-GPC offers 250 mg alpha GPC taken twice daily. It is made free from GMOs or gluten, and it does not contain any artificial preservatives or flavors.

Specs

  • 500 mg alpha GPC
  • Two capsules per serving
  • 30 servings per container
  • Non-GMO
  • Gluten-free
  • No artificial preservatives or flavors
  • Lower dosage per capsule
  • Pricey

Who Makes It?

Douglas Laboratories started in 1955 with nutrition pioneer Sam Lioon, who began selling nutritional supplements directly to healthcare professionals. Today, the company offers a variety of products available to consumers as well.

Bottom Line

Made with good alpha GPC and free from gluten, GMOs and many artificial ingredients, this is a top alpha GPC supplement. However, it offers a lower dosage per capsule then many alternatives, and it costs more.

7. Purisure Alpha-GPC Powder

Purisure Alpha Gpc Powder

Purisure Alpha-GPC Powder is a powder rather than a pill. It is a 50/50 blend of alpha GPC and silicon dioxide, a commonly used pharmaceutical and supplement ingredient that prevents the powder from sticking together.

Specs

  • 300 mg alpha GPC
  • 300 mg silicon dioxide
  • 42 servings per bag
  • Affordable
  • Money back guarantee
  • Good customer reviews
  • Not pure alpha GPC

Who Makes It?

Purisure is a natural health brand offering mostly nootropic supplement powders. The ingredients used are pure and sourced from around the world. The company offers a money back guarantee.

Bottom Line

This powder alpha GPC supplement offers dosing flexibility, and a great price point. However, it is half silicon dioxide, which is not necessarily beneficial.

8. Swanson Alpha-GPC

Swanson Alpha-Gpc

Swanson Alpha-GPC is a vegetarian supplement offering a good alpha GPC dosage of 300 mg per capsule. It is manufactured in a GMP certified facility, has guaranteed purity and potency and is supported by a 100% money back guarantee.

Specs

  • 300 mg alpha GPC
  • One capsule per serving
  • 60 servings per container
  • Vegetarian
  • GMP certified
  • Guaranteed purity and potency
  • 100% money back guarantee
  • Includes unnecessary added ingredients

Who Makes It?

Headquartered in Fargo, North Dakota, Swanson Vitamins is a dietary supplement brand that was founded in 1969. Its products are science-backed and provided at value prices.

Bottom Line

This basic alpha GPC pill provides vegetarian pills made in a GMP certified facility using guaranteed potent and pure alpha GPC. The company offers a 100% money back guarantee. However, it does include unnecessary added ingredients.

9. Pure Encapsulations – Alpha-GPC

Pure Encapsulations - Alpha-GPC

Pure Encapsulations – Alpha-GPC is a potent alpha GPC supplement. It is recommended to take two capsules three times daily for a total of 1200 mg per day.

Specs

  • 1200 mg alpha GPC
  • Two capsules per serving, three times daily
  • 30 servings (10 days’ worth)
  • Vegetarian
  • Gluten-free
  • No coatings
  • Small quantity
  • Pricey

Who Makes It?

Pure Encapsulations specializes in hypoallergenic health supplements developed using medical research and designed to deliver predictable results. The brand is trusted by medical professionals.

Bottom Line

One of the highest quality alpha GPC supplements available, this is also one of the most expensive. It’s a potent alpha GPC supplement, and recommended to take two pills three times daily. However, there are only ten days’ worth of pills in one container.

10. Powder City Alpha GPC

Powder City Alpha GPC

Powder City Alpha GPC is half silicon dioxide, half alpha GPC. It offers 300 mg of alpha GPC per serving, using guaranteed pure ingredients that is verified with third party laboratory testing.

Specs

  • 300 mg alpha GPC
  • 300 mg silicon dioxide
  • Two capsules per serving
  • 30 servings per container
  • Guaranteed purity
  • Third party lab tested
  • Not pure alpha GPC

Who Makes It?

Powder City offers bulk dietary supplements and nootropics to over 250 thousand worldwide. The company was founded in 2014.

Bottom Line

Offering 300 mg alpha GPC per serving, this supplement is a good option for many. It is third party lab tested and made with guaranteed pure ingredients. However, it isn’t pure alpha GPC, it’s half silicon dioxide.

What is Alpha GPC?

Alpha GPC is a compound found in food that the body uses for supporting basic health systems in the brain and nervous system.

Soybeans contain a fatty acid that, when broken down, releases this nootropic chemical known as alpha GPC. (1) It contains choline, an essential nutrient that supports metabolism and helps synthesize phospholipids that are vital for cell membranes. (2) Choline is the precursor to a neurotransmitter known as acetylcholine, which is an important messenger for the part of the nervous system that is involved in the contraction of muscles, and can also help to dilate blood vessels, slow the heart rate, and increase bodily secretions. (3, 4)

Alpha GPC is a prescription medication for Alzheimer’s disease in Europe, offered as a dietary supplement or a shot. In the United States, Alpha GPC is only available as a dietary supplement. (1)

Taken as a supplement, it may help prevent cognitive decline and it appears to support cell membranes. (5)

Alpha GPC appears to be active at higher dosages, and alpha GPC supplements can provide the body with additional choline ― it’s about 40% choline by weight. (5) Choline plays an important role in cognition, memory, mood, muscle control, and other brain and nervous system functions. (2)

There is a some promising research on alpha GPC’s benefits to human health, but more research is necessary.

What Are the Uses & Benefits of Alpha GPC?

Because of alpha GPC’s role in the brain and nervous system, there is interest in its use for both cognitive and athletic benefits. Its uses include:

  • Cognitive support: Alpha GPC supplements provide a high choline content, which is an important nutrient for cell membranes. It acts as a critical component of the cell membrane and supports cellular structure. (6) One large, double-blind study lasting over six months showed that alpha GPC supplements at dosages of 400 mg taken three times daily in persons with mild to moderate Alzheimer’s disease notably improved symptoms. The study included 261 human subjects of both genders in a placebo-controlled trial. (7) The same study showed that the rate of cognitive decline was significantly reduced.
  • Athletes: There is some interest in the use of alpha GPC supplements for enhancing production of growth hormone in athletes. Growth hormone can improve body composition (fat vs. muscle percentage by mass) and can support maximum power output. (8) One study found that seven trained men saw a 14% increase in power output, as well as an increase in exercise-induced growth hormone, when supplementing with 600 mg alpha GPC prior to exercise. (9) However, this study was funded by the company that produced the alpha GPC product being tested, so results might not be reliable.

How to Take Alpha GPC

Alpha GPC supplements have been taken at dosages between 300 and 1200 mg in scientific studies. (5) Larger dosages are typically used in studies of alpha GPC’s cognitive effects, and are split into 400 mg alpha GPC dosages taken three times daily. (7)

What Are the Side Effects of Alpha Gpc?

When taken at appropriate dosages, alpha GPC is a safe supplement. However, some people may experience side effects such as heartburn, headache, insomnia, dizziness and skin rash.

What to Look for in a Good Alpha GPC Supplement

Good alpha GPC supplements offer quality dosages of around 300 mg minimum per serving. They are also made by reliable companies with good reputations. Check the ingredients list on the back of alpha GPC supplements to make sure it does not contain unnecessary or harmful added ingredients.

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Austin Meadows

Written by Austin Meadows

Austin Meadows is an independent writer and consultant specializing in health and wellness topics. With more than 7 years of experience writing in the natural health industry, Austin strives to deliver accurate, concise and research based information to his readers. You can connect with him on LinkedIn.