Best Pyruvate Supplements – Top 10 Reviewed for 2018

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Jump Ahead to the Top 10 Pyruvate Supplements

What is Pyruvate?

Pyruvate, also known as pyruvic acid, is a chemical produced in the body during the process of glycolysis. Glycolysis involves the breakdown of glucose by enzymes. This process releases energy and pyruvate. Pyruvate plays an important role in the synthesis of amino acids such as alanine. It is also involved in cellular respiration and the synthesis of lipids and fatty acids.

Pyruvate is not an essential nutrient since your body typically makes all it needs. Natural sources of pyruvate include cheese, red wine, dark ale, and apples.

As a supplement, pyruvate is usually sold in the form of calcium pyruvate (the stabilized version of pyruvic acid). Calcium pyruvate is the compound responsible for initiating the Krebs cycle. This process involves the series of reactions in which cells produce energy during aerobic exercise.

Pyruvate Uses

There are a number of claims about calcium pyruvate benefits, particularly that the supplement can help increase physical endurance and weight loss. While the supplement shows promise in several areas, more research is needed.

  • Weight loss: Few clinical trials have been conducted to test the claim that calcium pyruvate boosts weight loss. One review and analysis of randomized trials assessed six out of a total of nine trials. The reviews claimed that all the studies were flawed by weaknesses in their methodology. Specifically, it was revealed that there was a significant difference in body weight with pyruvate compared to placebo. More research is needed to support the claim that calcium pyruvate promotes increases weight loss.
  • Physical endurance: A study conducted by researcher Ronald T. Stanko, MD at the University of Pittsburgh Medical Center revealed that subjects who were given pyruvate in combination with dihydroxyacetone (DHA), for a period of seven days, showed a significant increase in physical endurance in the legs and arms. Pyruvate is thought to potentially boost muscle performance by increasing glucose transportation to the muscles’ cells. However, this study looked at pyruvate combined with DHA, and therefore did not isolate the effects of pyruvate alone.
  • Alcoholic liver disease: Preliminary research suggests that giving calcium pyruvate intravenously for a period of 25 days may improve the liver functions of people suffering from alcoholic liver disease. More research is needed to confirm these findings. It’s unclear whether the oral supplement form will have the same effect or not.
  • Aging: There are some claims that calcium pyruvate has beneficial effects on the skin such as reducing the signs of aging and fighting against the damaging effects of the sun. There is insufficient clinical evidence to support these claims.

Calcium pyruvate has also been touted for chronic obstructive pulmonary disease (COPD), high cholesterol, and congestive heart failure. There is inconclusive evidence for taking a calcium pyruvate supplement for any of these disorders. Overall, this is a supplement that requires study in many more reputable clinical trials in order to prove its efficacy.

How to Take Pyruvate

There is no recommended pyruvate supplement dosage. Pyruvate nutritional supplements are typically offered as calcium pyruvate or sodium pyruvate. They are available in tablet, capsule or powder form. It can be taken with or without food. If you’re using the powdered bulk form, it can be mixed into liquids, shakes, or sprinkled on food.

As for the pyruvate dose, most suppliers of pyruvate recommend a daily dose of 2-5 grams of oral pyruvate per day. Although, Examine.com notes that most of the weight loss studies that have looked at pyruvate have used massive doses in the range of 6 to 50g per day. The ideal pyruvate dosage has not been officially established.

Pyruvate Side Effects and Precautions

Pyruvate is considered possibly safe when taken orally for a maximum of six weeks. Side effects may include upset stomach, bloating, gas, and diarrhea if large amounts are taken.

This is a supplement that has not been studied sufficiently. The potential benefits are unclear, and the long-term side effects and potential complications have not been firmly established. Caution is advised.

You should not take pyruvate if you are pregnant or breastfeed as not enough is known about the supplement’s effects in these cases.

Pyruvate should also be avoided if you suffer from the heart condition cardiomyopathy and other cardiac health issues.

Taking large doses of pyruvate could worsen cases of diarrhea and other digestive issues and may worsen the symptoms of IBS.

What to Look for in a Good Pyruvate Supplement

When you are looking for a good calcium pyruvate supplement, you should choose one which has an effective strength and that does not contain known allergens, artificial colors, preservatives or unnecessary fillers. The supplement should also provide good value for money and be made by a reputable company with rigid quality control standards.

Top 10 Pyruvate Products Compared

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1. Best Naturals Calcium Pyruvate

Best Naturals Calcium Pyruvate

Best Naturals Calcium Pyruvate provides 750 mg of calcium pyruvate per serving. These bottles contain 120 capsules. There are three available quantity options, all at very reasonable prices.

Specs

  • Each serving provides 750 mg of calcium pyruvate
  • Contains no artificial color, flavor or sweetener
  • Gluten-free
  • Contains no known common allergens
  • GMP certified

Who Makes It?

Best Naturals is based in New Jersey, they manufacture high quality dietary and nutritional supplements. They develop their own formulas, and all their products are made in a cGMP compliant environment.

Bottom Line

If you’re looking for good pyruvate pills, look no further. This is a strong formula for a good price.

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2. NOW Sports Pyruvate

NOW Sports PYRUVATE

NOW Sports Pyruvate provides 600 mg of pyruvate per serving. The bottle contains 100 capsules. This is a powerful pyruvate supplement made by a reputable company, and one of the better pyruvate supplements on the market today.

Specs

  • Provides 600 mg of calcium pyruvate per serving
  • Non-GMO
  • Good price
  • Good reviews
  • Not suitable for vegans or vegetarians

Who Makes It?

NOW is a family-owned American-based company which has been manufacturing nutritional supplements since 1968. They are dedicated to providing high-quality products and services to encourage people to lead healthier lives.

Bottom Line

This is a strong pyruvate supplement made by a reputable company. It offers great value for money and has good reviews.

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3. BulkSupplements Pure Calcium Pyruvate Powder

Bulksupplements Pure Calcium Pyruvate Powder

BulkSupplements Pure Calcium Pyruvate Powder is a sealed pouch offering a bulk supply of 250 grams of calcium pyruvate. It’s suitable for adding to drinks or making your own capsules.

Specs

  • 250 grams of calcium pyruvate pure powder
  • Contains no fillers
  • Factory-sealed foil zip pouch
  • Lab tested for verification
  • Guaranteed purity

Who Makes It?

BulkSupplements is located in Nevada, U.S.A. The company supplies more than 400 pure natural ingredients to both consumers and manufacturers. Each of their products is available in varying weights from grams to metric tons.

Bottom Line

This is a great supplement if you are looking for pyruvate to add to drinks or shakes. It is pure powder and is contained in a zip pouch, so you can easily reseal it to maintain freshness.

4. Piping Rock Health Products Calcium Pyruvate

Piping-Rock-Health-Products-Calcium-Pyruvate

Piping Rock Health Products Calcium Pyruvate provides 1000 mg of calcium pyruvate per serving. This offer is for two bottles, each containing 90 capsules.

Specs

  • Each serving contains 1000 mg of calcium pyruvate
  • Suitable for vegans and vegetarians
  • Contains fillers
  • Good price
  • Mixed reviews

Who Makes It?

Piping Rock is an American-based company that was formed in 2011. Their goal is to provide high-quality nutritional supplements which are affordable.

Bottom Line

This is a high-strength pyruvate supplement at an affordable price. Unfortunately, it contains fillers.

5. Pure Naturals Calcium Pyruvate

Pure Naturals Calcium Pyruvate

Pure Naturals Calcium Pyruvate provides 1500 mg of pyruvate per serving. The bottle contains 120 caps. The pills contain no known allergens.

Specs

  • Provides a powerful dose of 1500 mg of pyruvate per serving
  • Sodium-free
  • Contains no common allergens
  • Not suitable for vegans or vegetarians

Who Makes It?

This is an American-based company which began manufacturing nutritional supplements in 2014. All Pure Naturals products are manufactured in accordance with Good Manufacturing Practices and are Purity & Potency Guaranteed.

Bottom Line

This is one of the best pyruvate supplements on the market today. These are strong pyruvate pills and they are offered at a very reasonable price.

6. PureControl Supplements Calcium Pyruvate

PureControl Supplements Calcium Pyruvate

PureControl Supplements Calcium Pyruvate provides 750 mg of calcium pyruvate per serving. The bottle contains 240 capsules. The suggested dosage is 1 capsule per day.

Specs

  • Provides 750 mg of calcium pyruvate per serving
  • Not suitable for vegans or vegetarians
  • Contains fillers
  • Does not contain common allergens
  • Made in the USA

Who Makes It?

PureControl Supplements is a private label branding company that packages and resells third-party manufactured supplements.

Bottom Line

Although this supplement provides a good dose of calcium pyruvate, it does contain some fillers.

7. Solaray Calcium Pyruvate

Solaray Calcium Pyruvate

Solaray Calcium Pyruvate provides 600 mg of calcium pyruvate per serving. The bottle contains 100 caps. The suggested dose is one daily.

Specs

  • Provides 600 mg of calcium pyruvate per serving
  • Not suitable for vegans or vegetarians
  • Contains fillers
  • Mixed reviews

Who Makes It?

Solaray nutritional supplements are manufactured by Nutraceutical. The company is based in Utah and was launched in 1973. Solaray is their flagship brand.

Bottom Line

If you what a reasonably high dosage this is a good choice, that said, it does contain fillers.

8. Earth Natural Supplements Calcium Pyruvate

Earth Natural Supplements Calcium Pyruvate

Earth Natural Supplements Calcium Pyruvate provides 750 mg per serving. This offer has two bottles each containing 120 capsules.

Specs

  • Provides 750 mg per serving
  • Powerful pyruvate supplement
  • 2-bottle offer

Who Makes It?

Earth Natural Supplements is an American-based nutritional supplement manufacturer. Their aim is to produce quality supplements from potent natural ingredients.

Bottom Line

This supplement is a good strength and a reasonable price for the two bottles.

9. BioPower Calcium Pyruvate

BioPower Calcium Pyruvate

BioPower Calcium Pyruvate provides 750 mg of calcium pyruvate per serving. The bottle contains 120 capsules. The suggested dose is one to three capsules.

Specs

  • Provides 750 mg of calcium pyruvate per serving
  • Reputable manufacturer
  • Good reviews
  • Expensive

Who Makes It?

BioPower Nutrition is located in Arcadia, California. They manufacture a wide range of nutritional and dietary supplements.

Bottom Line

In spite of its strength, this is an expensive supplement for the number of caps provided.

10. Swanson Triple Pyruvate Electrolyte Complex

Swanson Triple Pyruvate Electrolyte Complex

Swanson Triple Pyruvate Electrolyte Complex provides 775 mg of calcium pyruvate. The bottle contains 60 caps.

Specs

  • Provides 775 mg of calcium pyruvate
  • Suitable for vegans and vegetarians
  • Good price
  • Contains fillers

Who Makes It?

Swanson Health has been manufacturing vitamins and nutritional supplements since 1969. Their aim is to deliver wellness solutions to help people live healthier lives.

Bottom Line

This supplement is great value for money, and it’s suitable for vegans. Unfortunately, it contains fillers.